Publications

2019

The Hippo Pathway, YAP/TAZ, and the Plasma Membrane. (Review) 2019, Trends in Cell Biology.

Disease and the Hippo Pathway. Hansen CG. (Editorial) on the completed Special Issue in Cells.

The Hippo Pathway in Prostate Cancer. Salem O and Hansen CG. (Review) 2019 Apr 23;8(4). pii: E370. doi: 10.3390/cells8040370. Cells.

The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Rausch V, Bostrom JR, Park J, Bravo IR, Feng Y, Hay DC, Link BA, Hansen CG. Volume 29, Issue 2, 21 January 2019, Pages 242-255.e6 Current Biology.

Immunofluorescence Study of Endogenous YAP in Mammalian Cells. (Book Chapter) Rausch V and Hansen CG.  2019;1893:97-106. doi: 10.1007/978-1-4939-8910-2_8 Methods Mol Biol.

2017

EHD proteins cooperate to generate caveolar clusters and to maintain caveolae during repeated mechanical stress.  Ivana, Y., Howard, G., chadwick, J., Mendoza, C., Hansen, C., Nichols, B. J. & Shvets, E. 9 Oct 2017 In : Current Biology.

2015

The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1.  Hansen, C. G., Ng, Y. L. D., Lam, W-L. M., Plouffe, S. W. & Guan, K-L. Dec 2015  . 25, 12, p. 1299-313 15. Cell Research .

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Meng, Z., Moroishi, T., Mottier-Pavie, V., Plouffe, S. W., Hansen, C. G., Hong, A. W., Park, H. W., Mo, J-S., Lu, W., Lu, S., Flores, F., Yu, F-X., Halder, G. & Guan, K-L. 5 Oct 20156, p. 8357 Nature Communications.

YAP and TAZ: a nexus for Hippo signaling and beyond (review) Hansen, C. G.^, Moroishi, T.^ & Guan, K-L. Sep 2015  25, 9, p. 499-513 15. Trends In Cell Biology.

Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids. Shvets, E., Bitsikas, V., Howard, G., Hansen, C. G. & Nichols, B. J. 21 Apr 2015 6, p. 6867. Nature Communications.

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Mo, J-S., Meng, Z., Kim, Y. C., Park, H. W., Hansen, C. G., Kim, S., Lim, D-S. & Guan, K-L. Apr 2015 In : 17, 4, p. 500-10 11 p. Nature Cell Biology.

The emerging roles of YAP and TAZ in cancer. (review) Moroishi, T^., Hansen, C. G^. & Guan, K-L. Feb 2015 In : 15, 2, p. 73-9 7 p. Nature Reviews Cancer.

2014

Cavin-3 knockout mice show that cavin-3 is not essential for caveolae formation, for maintenance of body composition, or for glucose tolerance Liu, L., Hansen, C. G., Honeyman, B. J., Nichols, B. J. & Pilch, P. F. 2014 In : PLoS One. 9, 7, p. e102935.

2013

Deletion of cavin genes reveals tissue-specific mechanisms for morphogenesis of endothelial caveolae Hansen, C. G., Shvets, E., Howard, G., Riento, K. & Nichols, B. J. 2013 In : Nature Communications. 4, p. 1831.

2011

Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis Hansen, C. G., Howard, G. & Nichols, B. J. 15 Aug 2011 In : Journal of Cell Science. 124, Pt 16, p. 2777-85 9 p.

2010

Exploring the caves: cavins, caveolins and caveolae Hansen, C. G. & Nichols, B. J. Apr 2010 In : Trends In Cell Biology. 20, 4, p. 177-86 10 p.

2009

SDPR induces membrane curvature and functions in the formation of caveolae Hansen, C. G., Bright, N. A., Howard, G. & Nichols, B. J. Jul 2009 In : Nature Cell Biology. 11, 7, p. 807-14 8 p.

Molecular mechanisms of clathrin-independent endocytosis Hansen, C. G. & Nichols, B. J. 1 Jun 2009 In : Journal of Cell Science. 122, Pt 11, p. 1713-21 9 p.

2008

Binding of serotonin to the human serotonin transporter. Molecular modeling and experimental validation Celik, L., Sinning, S., Severinsen, K., Hansen, C. G., Møller, M. S., Bols, M., Wiborg, O. & Schiøtt, B. 26 Mar 2008 In : Journal of the American Chemical Society. 130, 12, p. 3853-65 13 p.

2006 

Dissection of an allosteric mechanism on the serotonin transporter: a cross-species study Neubauer, H. A., Hansen, C. G. & Wiborg, O. Apr 2006 In : Molecular Pharmacology. 69, 4, p. 1242-50 9 p.