The TEAM

Meet the people behind the science.

Dr Carsten Gram Hansen

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I did my MSc in Aarhus, Denmark carrying out research on the serotonin transporter. I then moved to Cambridge to pursue a PhD with Dr Ben Nichols at the MRC- Laboratory of Molecular Biology in the Cell Biology division. Through a Lundbeck foundation Post Doctoral Fellowship I stayed on to maximise the output of my PhD findings. After a six-year stint in Cambridge, via a Post Doctoral Fellowship from the Danish Science Foundation I moved to San Diego to work with Professor Kun-Liang Guan. While there I studied the cellular signalling pathway called the Hippo Pathway. In Nov 2015 I was recruited to the University of Edinburgh Centre for Inflammation Research on a Chancellor’s Fellowship to set up a new lab. I am now a Senior Lecturer.

I am pleased that our team is diverse, international and that all are great team citizens. Through our shared interest in discovery based inter disciplinary Science, we seek to address fundamental biological questions. We strive to be challenged and to make important discoveries, but also seek to have fun along the way.

 

Susanna Riley – PhD student (2019 -)

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Originally from rural West England, I completed a BA (Hons) in Cell and Systems Biology at the University of Oxford in 2017 before moving to the University of Edinburgh for an MSc by Research in Biomedical Sciences. I then began the Wellcome Trust PhD programme in Tissue Repair. My research in the Gram Hansen lab focusses on the role of the Hippo pathway in embryonic development and regeneration using the zebrafish.

Read about Susanna’s work

Dr Richard Cunningham – Post Doc (2019 -)

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After completing my undergraduate studies at Trinity College Dublin, I came to Scotland where I obtained my MSc in Bioinformatics at the University of Glasgow. I stayed on in Glasgow, subsequently carrying out my PhD in Professor Andrew Biankin’s group, exploring the potential in targeting tumour metabolism in pancreatic cancer. As part of the Gram Hansen lab, my research is centred on disentangling the role of the Hippo pathway in the formation and progression of malignant pleural mesothelioma.

Read about Ricky’s work

https://doi.org/10.1038/s43018-021-00259-9

DOI: 10.1126/sciimmunol.abj2132

doi.org/10.1042/CS20201474

Krishna Purohit – PhD student  (Sep 2020 – )

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I have a BSc honours in Biochemistry and hold masters in Biochemistry (University of Edinburgh) and Bioinformatics and System Biology (University of Manchester). As part of the MRC Precision Medicine DTP my PhD project in the Gram Hansen lab focuses on investigating the role of cancer mutations using a novel omics technique called proteogenomics, with the aim of stratifying diagnosis and treatments for mesothelioma patients.

Read about Krishna’s work here and

https://doi.org/10.1038/s43018-021-00259-9

Siyang Jia – PhD student 2021 –

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Sijang was a MSc student with us and is now back for more! Siyang is part funded by the CSC and is studying how the Hippo pathway regulates cancer onset and development. 

Read about Siyang’s work

Here, Here and Here

 

Nancy Hui PhD Student July 2022 –

Nancy is part of the Martin Lee PhD program and is studying how the Hippo pathway modulates ageing.

Read about Nancy’s work here

Michaela Noskova PhD Student Sep 2022 –

Michaela is a Prec Medicine PhD student and developing zenograft model systems.

Work from Michaela (from previous lab, but nonetheless beautiful!)

Lisa Kölln – PhD student (2017-)

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(Based at the University of Strathclyde, Prof. Gail McConnell lab

In my PhD project I am investigating the Hippo pathway in Malignant Mesothelioma. For that I use advanced imaging techniques in the lab of Prof Gail McConnell at the University of Strathclyde. Before I moved to Scotland, I finished my Master’s degree in Physics at the University of Potsdam.

Read about Lisa’s work

and more

——————-Alumni—————–

Dr Omar M. Salem – MSc (2018), PhD student (2018-2021), and Post Doc 2022

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“Born and raised in Egypt, I moved to the UK to continue my undergraduate studies. I received a First Class BSc (Hons) in Cell Biology from the University of Stirling. I later joined the University of Edinburgh for a MSc by Research in Biomedical Sciences. My PhD project (2018-2021) at the Gram Hansen lab was focused on studying the Hippo pathway regulation of Prostate Cancer development, progression and metastasis. He also worked on the Hippo pathway as a therapeutic target.”

Read about Omar’s work, here and here

Dr Salem went onto work as a Researcher at Artios, Cambridge UK

Dr Jiwon Park – PhD student (2017 – 2021)

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“My research focused on the role of mechanotransduction signals in relation to the Hippo pathway. I completed my undergraduate degree in BSc (Hons) Biomedical sciences (Pharmacology) at the University of Edinburgh in 2017. After graduating, I started on the  MRC-funded Precision Medicine Doctoral Training Programme in the Gram Hansen Lab. “

Read about Jiwon’s work doi: 10.1016/j.cub.2018.11.066

doi.org/10.1042/BST20200253

https://doi.org/10.15252/embj.2021108719

Dr Park then moved onto becoming a Patent attorney at Marks & Clerk.

Dr Valentina Rausch – PhD Student (2016 – 2019)

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Alumni of the Gram Hansen Lab, revealed the interaction between the Hippo pathway and caveolae. Dr Rausch was the first PhD student in the lab, and handed her thesis in after 3 years and 18 days! Then moved onto an academic Post Doc.

Read about Valentina’s work while in Edinburgh

DOI: 10.1016/j.cub.2018.11.066,

DOI: 10.1007/978-1-4939-8910-2_8.

DOI: 10.1128/mBio.02857-19.

DOI:https://doi.org/10.1016/j.tcb.2019.10.005.

 
MSc and Honours
  • 2022 Shijia Lin MScR 2nd project Biomedical Sciences. Obtained overall a distinction. Now in Singapore for her PhD.
  • 2022 Yue Lin MScR 2nd project, Biomedical Sciences. Also stayed on with us as an intern for three months. Currently applying for PhD positions. Read about Yue’s work here
  • 2020 Jon Corres (MScR) 2nd Project. Obtained overall a Distinction. Then moved on for a PhD student back in Spain.
  • 2020 Josh Martin (MScR) 2nd Project. Obtained overall a Distinction. Then moved on for a PhD student at BARTS Cancer Center.
  • 2019-2020 Emelie Shepherd (MScR) 1st Project. Obtained overall a Distinction.
  • 2018 Duncan Maclean (Honours student), then moved on to continuing his Medicine Degree at the University of Edinburgh.
  • 2017 Tamara Hussain (Honours student), moved onto working at Charles River.

SUMMER INTERN

Michael Marcin, Summer Intern 2022. Awarded a Biochemical Society Stipend.